EDTA Trisodium Gel 24% (Root Canal Chelating Agent)
Dental Supplies

EDTA Trisodium Gel 24% (Root Canal Chelating Agent)

Pack Sizes Available

Syringe: 5ml or 10ml (specify at order)
Includes irrigation needle(s)
Bottle format also available for bulk use

Product Description

Root canal instrumentation produces a smear layer. This is not a defect or a complication. It is simply what happens when NiTi or stainless steel files abrade the dentinal walls of the canal during shaping — a mixture of organic material, bacteria, and inorganic dentin particles that coats the canal walls and partially occludes the dentinal tubule entrances. Whether this smear layer should be removed before obturation is a long-running debate in endodontics, but the clinicians and the guidelines who advocate for its removal are clear about why: a canal obturated over an intact smear layer has a less predictable seal, because the filling material bonds to the smear layer rather than to the underlying clean dentin surface. EDTA (Ethylenediaminetetraacetic acid) is the chelating agent of choice for smear layer removal and for canal calcification management. In its 24% trisodium salt gel formulation, it provides two clinical functions simultaneously: the chelating action demineralises the inorganic component of the smear layer and softens calcified canal sections, while the gel carrier keeps the active ingredient at the site of action — on the canal walls — rather than immediately washing out with the next irrigant exchange. In the endodontic working sequence, EDTA gel is placed into the canal before and during instrumentation. It acts as a lubricant that reduces the friction between the file and the canal wall, which is particularly important in narrow, curved, or calcified canals where file binding risks transportation or separation. During the final irrigation sequence, a final 1-minute rinse with liquid EDTA 17% (or an EDTA-NaOCl alternating protocol) is used to thoroughly remove the smear layer before the drying and obturation steps. For dental distributors supplying endodontic practices, EDTA gel is a consistently purchased consumable used in virtually every root canal case. Single-dose or multi-dose syringe formats cover both clinical preferences. Sara Wellness exports endodontic irrigants and chelating agents to dental distributors internationally.

Technical Specifications

  • Active Ingredient: EDTA Trisodium (tripotassium) salt — 24% concentration
  • Form: Viscous gel — with irrigation needle for direct canal placement
  • Available Pack Sizes: 5ml syringe; 10ml syringe; bottle format for bulk use
  • Clinical Functions: Smear layer removal (inorganic component); calcification chelation; canal lubrication during instrumentation
  • Use in Protocol: Applied during instrumentation; final irrigant flush sequence before obturation
  • Compatibility: Not to be mixed directly with sodium hypochlorite — use alternating flush protocol
FAQ

Frequently asked questions

EDTA gel (17% or 24% in a viscous carrier) is used during instrumentation as a lubricant and chelating agent applied directly into the canal on the file. The gel consistency keeps the EDTA at the canal wall surface during filing strokes, providing continuous chelation and lubrication. EDTA liquid (typically 17% solution) is used as an irrigant during and after instrumentation, either as an alternating flush with sodium hypochlorite or as the final rinse before drying. The gel is more effective for lubrication during filing; the liquid is more effective for thorough smear layer removal during the final irrigation protocol.

EDTA is available in various concentrations ranging from 15% to 24%. Higher concentration EDTA has a greater chelating capacity per unit volume and achieves effective dentinal demineralisation in a shorter contact time, which is clinically relevant when the file is only in contact with the gel for the duration of each filing stroke. The 24% trisodium EDTA formulation is particularly effective for calcified canals and resistant smear layers. However, extended contact with 24% EDTA can cause excessive dentin demineralisation that weakens root structure, so the final rinse protocol and contact time recommendations should be followed.

No. EDTA and sodium hypochlorite (NaOCl) should not be mixed simultaneously in the canal or in the same irrigant syringe. The combination causes a precipitate (calcium hypochlorite) and inactivates both agents, significantly reducing the antimicrobial effectiveness of the NaOCl and the chelating effectiveness of the EDTA. The correct protocol is to use alternating flushes: NaOCl, followed by flushing with sterile saline or water to remove the NaOCl, then EDTA, then NaOCl again — never directly combining them in the canal.

EDTA gel is placed into the canal access cavity using the included irrigation needle before each file size is used. A small amount (approximately 0.1-0.2ml) is placed in the canal, and the file is worked through the gel as it is advanced to working length. The gel is refreshed between file size changes and flushed out before the final obturation irrigation sequence. It can also be placed on the file tip before insertion to provide immediate lubrication as the file enters the canal in tight or calcified cases.

EDTA gel should not be extruded beyond the apical foramen into the periapical tissues, as it can cause periapical irritation and delayed healing if expressed into the periradicular area. The working length must be accurately confirmed before irrigation with EDTA to ensure the irrigant is being placed within the canal. In cases where the apex is open (open apex due to immature development or resorption), EDTA should be used with particular caution and minimal apical pressure during irrigation.

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