Ethicon Vicryl Plus Antibacterial Suture USP 1, 1/2 Circle Round Body (VP2350)
Surgical Sutures

Ethicon Vicryl Plus Antibacterial Suture USP 1, 1/2 Circle Round Body (VP2350)

Pack Sizes Available

Box of 12 sutures — model VP2350

Product Description

Post-operative wound infection is the variable that surgeons, infection control teams, and hospital administrators have been working to reduce for as long as there have been metrics to track it. Antibiotic prophylaxis covers the systemic side. Skin preparation covers the surface. What has traditionally received less attention is the suture surface itself — a several-centimetre length of braided synthetic material sitting in the wound, exposed to whatever bacteria are present in the operative environment, providing an interstice-rich surface that bacteria can use to establish biofilm before the host inflammatory response can clear them. Ethicon Vicryl Plus is Coated VICRYL (polyglactin 910) suture — the same braided absorbable suture that has been the standard for general soft tissue closure for decades — with the addition of triclosan coating. Triclosan is a broad-spectrum bacteriostatic agent that inhibits bacterial fatty acid synthesis, preventing bacteria from establishing colonisation on the suture surface during the first critical post-operative weeks. VP2350 is USP size 1 (EP 4), violet braided, with a 36-40mm 1/2 circle round body needle and a 90-120cm strand length — a large, heavy suture format designed for major fascial closures, uterine wall closure in caesarean section, bowel anastomosis, and deep abdominal tissue approximation where both tissue support and infection risk management are clinical priorities. The suture maintains the Vicryl absorption profile: 75% tensile strength at 14 days, 50% at 21 days, 25% at 28 days, with complete mass absorption between 56 and 70 days. The braided structure provides the excellent handling and knot security that has made Vicryl the high-volume standard for obstetric, general, and gynaecological surgery. Clinical evidence for triclosan-coated sutures shows approximately 30% reduction in SSI risk across a large meta-analysis, with NICE (UK) recommending triclosan-coated sutures as part of the SSI prevention bundle. Sara Wellness exports Ethicon sutures to surgical distributors internationally.

Technical Specifications

  • Material: Polyglactin 910 braided (90% glycolide, 10% L-lactide) + triclosan (IRGACARE MP) antibacterial coating
  • Model Code: VP2350
  • Suture Specification: USP size 1 (EP 4), violet braided, 90-120cm strand
  • Needle: 36-40mm, 1/2 circle, round body — for major fascial and deep tissue closure
  • Strength Retention: 75% at 14 days; 50% at 21 days; 25% at 28 days
  • Absorption: 56-70 days (average 63 days) complete mass absorption by hydrolysis
FAQ

Frequently asked questions

The evidence base for triclosan-coated sutures is substantial. A meta-analysis by de Jonge et al. published in the British Journal of Surgery (2017) analysed 31 randomised controlled trials with over 14,000 patients and demonstrated approximately 30% reduction in SSI risk with triclosan-coated sutures compared to non-coated equivalents. This is Level 1A evidence — the strongest classification in clinical evidence grading. Based on this data, NICE (National Institute for Health and Care Excellence, UK) issued recommendations in 2021 supporting triclosan-coated sutures as part of the SSI prevention bundle in surgical practice.

In vitro studies demonstrate that the triclosan coating on Vicryl Plus inhibits colonisation by the most common pathogens associated with surgical site infections: Staphylococcus aureus (including MRSA — methicillin-resistant strains), Staphylococcus epidermidis (including MRSE), Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis. The antibacterial activity has been shown to persist for 7-14 days after implantation, covering the critical early post-operative window when SSI risk is highest.

Vicryl Plus follows the same absorption profile as standard Coated VICRYL: approximately 75% tensile strength retention at 14 days, 50% at 21 days, and 25% at 28 days post-implantation. Complete mass absorption by hydrolysis occurs between 56 and 70 days (average approximately 63 days). This profile provides adequate wound support through the primary healing phase, after which the suture is progressively absorbed without the need for suture removal. The triclosan coating does not affect the absorption timeline or mechanical properties of the underlying polyglactin 910 suture.

Vicryl Plus USP 1 on a round body needle is indicated for major abdominal fascial closure, uterine wall closure in caesarean section, bowel and colon anastomosis, deep abdominal wall repair, and any application where large-calibre absorbable suture with antibacterial protection is appropriate. The USP 1 size provides the tensile strength for closure of substantial tissue layers under mechanical load, while the absorbable nature eliminates permanent foreign body in the wound after healing is complete.

The handling characteristics of Vicryl Plus are identical to standard Coated VICRYL. The triclosan is applied as a surface coating that does not alter the thread structure, coating, or needle characteristics of the suture. Surgeons who regularly use Coated VICRYL will not notice any difference in tissue passage, knot security, pliability, or needle performance when switching to Vicryl Plus. This is confirmed in published clinical data comparing the two products.

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