Hydrocortisone Sodium Succinate for Injection 200mg
Injectable Range

Hydrocortisone Sodium Succinate for Injection 200mg

Pack Sizes Available

200mg vial with 5ml Water for Injection ampoule
200mg single vial (bulk pack, diluent supplied separately)
Box of 10 vials for hospital and ICU stock

Product Description

When a patient's body suddenly can't produce its own cortisol, whether from adrenal crisis, severe sepsis, or an anaphylactic reaction spiralling out of control, there's no time to wait for an oral tablet to be absorbed. Hydrocortisone Sodium Succinate exists for exactly this moment, and the 200mg strength covers the higher end of typical emergency dosing without requiring a nurse to draw from two vials during a code. This is the water-soluble sodium succinate ester of hydrocortisone, chosen specifically because it dissolves fast and allows a high dose to be delivered in a small volume of diluent, which matters when every minute counts in an acute allergic reaction or adrenal insufficiency crisis. Once reconstituted, it can be given as a direct IV push or added to an IV bag for infusion, and its effects become measurable within about an hour, a timeline that matters a great deal in critical care. Beyond emergency use, this strength shows up regularly in the management of severe asthma exacerbations, transfusion reactions, and a range of autoimmune and dermatologic conditions where a short but intense course of systemic corticosteroid is needed. Because it's one of the more frequently stocked emergency drugs across ICUs, ERs, and ambulance services, consistent availability matters more here than almost any other line in a critical care catalogue, since a stockout on hydrocortisone is a stockout on something a hospital genuinely cannot substitute quickly. Manufacturing this molecule to a consistent standard requires careful pH control during reconstitution and stable lyophilization, since the succinate ester is sensitive to degradation if handling isn't tight throughout the production chain. We source exclusively from WHO-GMP certified manufacturers who maintain that discipline, and every export batch carries full documentation, certificate of analysis, and stability data, because emergency drug procurement teams check this paperwork with particular care given how often the product ends up in a life-or-death situation. We keep minimum order quantities flexible enough that a regional distributor supplying a handful of hospitals can maintain adequate emergency stock without warehousing volumes better suited to a national tender. After 15 years exporting critical care injectables from India, we've found that the buyers who reorder this product most consistently value a supplier who answers questions about batch traceability and lead times directly, without routing every query through layers of account management. For hospital pharmacies, emergency departments, and critical care wholesalers, Hydrocortisone Sodium Succinate 200mg fills one of the genuinely irreplaceable slots on an emergency drug formulary.

Technical Specifications

  • Active Ingredient: Hydrocortisone Sodium Succinate USP equivalent to 200mg Hydrocortisone
  • Dosage Form: Lyophilized powder for reconstitution
  • Administration Route: Intravenous (push or infusion) or intramuscular
  • Drug Class: Glucocorticoid corticosteroid
  • Reconstitution Diluent: Sterile Water for Injection, typically 5ml
  • Onset of Action: Approximately 1 hour after IV administration
  • Storage Condition: Store at 20 to 25 degrees C, protect from light
  • Shelf Life: 24 to 36 months from date of manufacture
FAQ

Frequently asked questions

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It is used in emergency situations requiring rapid corticosteroid action, including severe allergic reactions, anaphylaxis, adrenal crisis, acute asthma exacerbations, and transfusion reactions. It is also used in the management of certain severe dermatologic and autoimmune conditions when oral therapy isn't practical.

Measurable anti-inflammatory and physiological effects typically appear within about one hour of intravenous administration, though the duration of action varies depending on the condition being treated and the dose given. It is prized precisely for this fast onset in emergency settings.

Yes, unlike many corticosteroid formulations, hydrocortisone sodium succinate can be administered as a direct intravenous injection or added to compatible IV fluids for infusion, which is part of why it remains a preferred choice in emergencies where speed matters.

In situations requiring sustained high cortisol levels, injections may be repeated every 4 to 6 hours as the excretion of the administered dose is nearly complete within 12 hours. The treating physician determines the exact repeat schedule based on the clinical picture.

Caution is needed in patients with existing infections, uncontrolled diabetes, peptic ulcer disease, or congestive heart failure, since corticosteroids can mask signs of infection and cause fluid retention. Long-term or repeated use requires monitoring for the broader range of corticosteroid-related side effects.

The reconstituted solution is generally stable for several hours at controlled room temperature and can be administered directly or via IV piggyback, but it should not be autoclaved and any unused solution should be discarded rather than stored for a later dose.

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