Ampicillin & Cloxacillin Injection 500mg
Anti-Infectives & Antibiotics

Ampicillin & Cloxacillin Injection 500mg

Pack Sizes Available

1 Vial per Box (Ampicillin 500mg + Cloxacillin 500mg, powder for injection)
10 Vials per Export Carton
Reconstitution: Sterile Water for Injection as per required volume

Product Description

Staphylococcus aureus has a trick that plain ampicillin can't counter on its own: it produces penicillinase, an enzyme that breaks the antibiotic down before it can do any damage to the bacterial cell wall. Cloxacillin doesn't have that weakness. It's penicillinase-resistant by design, which is exactly why pairing it with ampicillin creates a combination that covers a wider spread of bacteria than either drug manages alone, gram-positive staph included. This fixed-dose combination injection is a fixture in general ward and outpatient antibiotic protocols across South Asia, the Middle East, and parts of Africa, where it's prescribed for everything from skin and soft tissue infections to respiratory tract infections and post-surgical prophylaxis. Each vial supplies ampicillin and cloxacillin in equal or matched proportions as sterile powder, ready for reconstitution before intramuscular or intravenous use. We've been producing and exporting this combination for years now, and the demand pattern tells its own story. Government tender buyers want consistent batch quality above almost everything else, because a tender contract that gets flagged for a quality deviation is a headache nobody wants twice. Private distributors care more about turnaround speed and MOQ flexibility, since they're often testing new SKUs in smaller quantities before committing to a bigger order. We structure our process to satisfy both. Every batch is manufactured under WHO-GMP conditions with documentation prepared in advance, not scrambled together after a buyer asks. Certificate of Analysis, stability reports, Free Sale Certificate, and whatever country-specific registration support you need, we keep it ready. That preparation matters more in this category than most, because antibiotic tenders and import registrations tend to move on tight timelines with little tolerance for missing paperwork. Packing comes standard as single vials per box or ten-vial cartons for bulk shipments, and we can adjust based on how your logistics chain actually handles pharma cargo. Pricing scales with order size in a way that rewards genuine volume commitments rather than penalizing smaller first orders, since we'd rather earn a long relationship than squeeze margin out of a trial shipment. Communication is kept direct and personal. You'll deal with one point of contact who knows your order history, your preferred documentation format, and your delivery expectations, rather than being routed through a rotating cast of account managers. After fifteen years of doing this, we've found that's the part buyers actually remember and come back for. If Ampicillin & Cloxacillin fits into your current or planned antibiotic range, reach out with your target quantity and destination country, and we'll get a formal quote back to you quickly.

Technical Specifications

  • Composition: Ampicillin + Cloxacillin, combined strength 500mg per vial, sterile powder
  • Dosage Form: Powder for injection, for reconstitution
  • Route of Administration: Intramuscular (IM) or Intravenous (IV)
  • Reconstitution Diluent: Sterile Water for Injection
  • Appearance: White to off-white sterile powder
  • Storage Conditions: Store in a cool, dry place, protected from light
  • Shelf Life: 24 months from date of manufacture
  • Packaging: 1 vial per box (standard) or 10 vials per export carton
FAQ

Frequently asked questions

Contact Export TeamContact Export Team

This combination is used for bacterial infections involving both ampicillin-susceptible organisms and penicillinase-producing Staphylococcus aureus, including skin and soft tissue infections, respiratory tract infections, and surgical prophylaxis. The cloxacillin component specifically protects against enzyme-mediated resistance from staph bacteria.

Ampicillin covers a broad range of gram-positive and gram-negative bacteria but is broken down by penicillinase enzymes produced by resistant staph strains. Cloxacillin is penicillinase-resistant and remains active against those strains, so combining the two extends coverage without needing two separate injections.

Each vial contains Ampicillin and Cloxacillin in matched proportions totaling 500mg combined strength, though formulations available in the market also include 250mg + 250mg splits depending on the specific brand and manufacturer. Buyers should confirm the exact ratio required for their market registration.

The sterile powder is reconstituted with the recommended volume of Sterile Water for Injection immediately before administration, either by intramuscular or intravenous route as directed by the prescribing physician. The reconstituted solution should be used promptly and not stored for extended periods.

Yes, this is a commonly tendered antibiotic in several export markets, and we prepare batches with the consistent documentation, COA, and regulatory support that tender processes typically require. We can also assist with country-specific registration documents on request.

Standard export packaging includes single vials per box or ten-vial cartons for bulk orders. MOQs are kept flexible and are adjusted based on the destination market and order type, whether it's a first trial shipment or a recurring bulk supply contract.

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