Acyclovir Tablets IP 400mg
Antivirals

Acyclovir Tablets IP 400mg

Pack Sizes Available

Blister Strip: 10 x 10 Tablets
Blister Strip: 3 x 10 Tablets
Export Carton: 100 x 10 Tablets

Product Description

Twice-daily dosing changes everything about whether a patient actually completes a long treatment course, and that's precisely the role the 400mg Acyclovir tablet plays. Where the 200mg strength asks for five doses a day, this strength is built around the twice-daily regimens used for chronic suppressive therapy, a meaningfully easier ask for someone managing recurrent outbreaks over months rather than days. Each tablet contains 400mg of Acyclovir, working through the same mechanism across every strength in the range: selective inhibition of viral DNA polymerase after activation inside an infected cell, which halts replication of herpes simplex virus and varicella-zoster virus without meaningfully affecting healthy, uninfected cells. That selectivity is a large part of why Acyclovir has stayed such a well-tolerated antiviral across decades of widespread global use. This strength is commonly used for chronic suppressive therapy in patients with frequent recurrent genital herpes, typically dosed at 400mg twice daily for extended periods, sometimes up to twelve months before re-evaluation. It's also used in episodic treatment regimens for recurrent outbreaks and in various treatment protocols for herpes-related conditions where a more moderate, twice-daily dose fits the clinical picture better than the higher-frequency 200mg schedule. For a distributor stocking a complete antiviral range, the 400mg strength tends to be the highest-volume mover of the three Acyclovir options simply because chronic suppressive therapy accounts for a large share of ongoing prescriptions, compared to the shorter, acute-episode courses that the other strengths are more often used for. We manufacture this strength to WHO-GMP standards alongside the 200mg and 800mg tablets, with contract manufacturing available under a buyer's own brand. Fifteen years of exporting antiviral formulations from India means this product ships with complete stability and bioequivalence documentation, not a partial file.

Technical Specifications

  • Active Ingredient: Acyclovir IP 400mg per tablet
  • Dosage Form: Tablet
  • Drug Class: Synthetic Purine Nucleoside Analogue (Antiviral)
  • Mechanism: Inhibits viral DNA polymerase, halting herpesvirus replication
  • Common Use: Chronic suppressive therapy for recurrent genital herpes (twice daily dosing)
  • Shelf Life: 24 months from date of manufacture
FAQ

Frequently asked questions

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It is commonly used for chronic suppressive therapy in patients with frequent recurrent genital herpes, typically dosed twice daily over an extended period, as well as for episodic treatment of recurrent outbreaks.

The 400mg strength is generally dosed twice daily for suppressive therapy, compared to the more frequent five-times-daily regimen typically used with the 200mg strength for acute episodes, making it more practical for long-term use.

Suppressive therapy regimens have been used for up to twelve months before re-evaluation by the prescribing physician, based on individual outbreak frequency and treatment response.

Suppressive therapy can reduce the frequency of outbreaks and viral shedding, but it does not eliminate the risk of transmission entirely; patients should follow their physician's guidance on additional precautions.

Commonly reported side effects include nausea, headache, and diarrhea; more significant effects such as renal impairment are rare and more commonly associated with intravenous administration or pre-existing kidney conditions.

Yes, WHO-GMP manufacturing with full documentation is available under a buyer's own brand, alongside the 200mg and 800mg strengths.

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The 500mg strength is where Acyclovir for Injection earns its place as a genuine hospital workhorse, the dose most commonly reached for when treating adult patients with severe herpes simplex or varicella-zoster infections that demand fast, dependable intravenous therapy. Whether that is a case of herpes encephalitis, severe genital herpes in an immunocompetent patient, or complications from shingles in someone whose immune system is already compromised, this is the strength most hospital protocols are built around. Acyclovir remains one of the more elegantly targeted antivirals available, precisely because it depends on a viral enzyme to activate itself inside infected cells, largely sparing healthy tissue from the same effect. Once active, it blocks the viral DNA polymerase and halts replication of the herpes virus at the molecular level. Despite decades on the market and newer antivirals entering the field, this mechanism has kept Acyclovir relevant across pediatric, adult, and geriatric hospital populations alike. Sara Wellness has supplied antiviral injectables like this one to hospital networks and distributors across multiple continents for fifteen years, and one lesson that has stuck with us the whole way through is that demand for antivirals rarely follows a predictable calendar. A shingles outbreak in a nursing home, an unexpected cluster of encephalitis cases, or simply a hospital rebuilding its critical care reserve after a tender cycle can all create sudden spikes in order volume, and a supplier who cannot respond quickly is a liability rather than a partner. We source this product from GMP-certified manufacturing facilities in India and keep a direct line between our export desk and the procurement teams we work with, so when volumes need to shift quickly, that conversation happens fast and without unnecessary back and forth. Our MOQs work for hospital pharmacies maintaining a standing reserve as well as distributors placing larger, tender-driven orders on a fixed schedule. Every consignment ships with certificate of analysis, GMP compliance documentation, and export paperwork prepared according to your destination country's specific regulatory expectations, because a held-up shipment of an antiviral needed for a severe infection is not a problem anyone wants to explain to a hospital's infectious disease team. If your formulary needs a dependable source for Acyclovir 500mg, or you are simply looking to diversify your antiviral supply chain, reach out with your target market and volume requirements and we will respond with current pricing and realistic delivery timelines based on actual production capacity.

Acyclovir for Injection 250mg
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Acyclovir for Injection 250mg

Herpesvirus infections do not announce themselves politely, and when they show up in a severe form, whether that is herpes simplex encephalitis, disseminated infection in a newborn, or a severe outbreak in an immunocompromised patient, oral treatment is often not fast or reliable enough. Acyclovir for Injection 250mg exists for exactly those moments, delivering a synthetic nucleoside analog directly into the bloodstream where it can start blocking viral DNA replication without waiting on gut absorption. The mechanism is elegant in its selectivity. Acyclovir gets converted into its active form far more efficiently inside cells infected by herpes simplex or varicella-zoster virus than in healthy cells, because it depends on a viral enzyme to kick off that conversion. Once activated, it interferes with viral DNA polymerase and gets incorporated into the growing viral DNA chain, effectively stopping replication in its tracks. That selectivity is a big part of why this molecule has remained a mainstay antiviral for decades despite newer options entering the market. For pediatric hospitals, neonatal ICUs, and general hospital pharmacies handling immunocompromised patients, the 250mg strength offers a smaller, more precisely dosable option, particularly useful in lower body weight patients where the full 500mg or 1000mg vials would require partial dosing and waste. Sara Wellness supplies this presentation from GMP-certified Indian manufacturing facilities as part of our broader antiviral and critical care injectable portfolio. Fifteen years in pharmaceutical export has taught us that antiviral demand tends to spike unpredictably, whether that is a seasonal herpes zoster wave or a broader viral outbreak straining hospital resources, and a supplier who cannot flex production or shipping schedules during those moments is not much use to a hospital network. We keep communication direct between our export team and your procurement staff, so if demand suddenly shifts, you are talking to someone who can actually adjust the order, not waiting on a call center to escalate. Every batch comes with certificate of analysis, GMP compliance documentation, and export paperwork built around your destination country's specific import requirements. Minimum order quantities are set to work comfortably for both a hospital pharmacy building a small antiviral reserve and a distributor supplying multiple hospital networks across a region. If your current antiviral supply chain has gaps, or you simply want a second reliable source out of India, reach out with your target country and expected volumes and we will respond with current pricing and honest delivery timelines.

Acyclovir Tablets IP 200mg
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Acyclovir Tablets IP 200mg

Herpes infections don't follow a single dosing pattern, which is why Acyclovir comes in three separate tablet strengths rather than one. The 200mg tablet is the workhorse of that range, built around a dosing regimen that asks for more frequent, smaller doses rather than fewer, larger ones, matched to how certain herpes treatment protocols are actually structured. Each tablet contains 200mg of Acyclovir, a synthetic purine nucleoside analogue with activity against herpes simplex virus types 1 and 2, along with varicella-zoster virus. Once inside a virus-infected cell, Acyclovir is converted to its active triphosphate form, which then inhibits viral DNA polymerase and gets incorporated into the growing viral DNA chain, effectively stopping viral replication in its tracks. Because this activation step depends on a viral enzyme, the drug is selectively active against infected cells rather than healthy ones, which is part of why it's remained a well-tolerated antiviral across decades of use. This strength is indicated for the treatment of initial and recurrent genital herpes episodes, where dosing regimens commonly call for 200mg taken five times daily for a defined treatment course, and for chickenpox treatment in appropriate patients. The frequent dosing schedule at this strength reflects Acyclovir's relatively short half-life and the need to maintain effective drug levels between doses. Acyclovir remains one of the most established antivirals in any pharmaceutical export portfolio, with steady, predictable demand across nearly every market given how common herpes simplex and varicella-zoster infections are worldwide. It's a category where consistent, uninterrupted supply matters more to a distributor than aggressive pricing on a single shipment. We manufacture all three Acyclovir tablet strengths to WHO-GMP standards, giving buyers a complete dosing range to offer prescribers rather than a single SKU. Contract manufacturing under a buyer's own brand is available, backed by fifteen years of exporting antiviral formulations from India with documentation built for the destination market's actual registration requirements.